Breast cancer risk and epigenetic effects of the rotating night shift work and lifestyle.

Project promoter

The promoter of this project is Nofer Institute of Occupational Medicine (NIOM), Łódź, Poland.

NIOM is a large institute (about 400 full time employees, 15 Departments, including 3 Clinics) established in 1954. The Institute hasclose collaboration with WHO acting since 1976 as the Collaborating Centre for Occupational Health. NIOM has also maintained links with many international institutions: ICOH, EDICHEM, IARC, EUROTOX, ACGIH, EUPHA, ASPHER, EASOM, IUPAC, the University of Iowa, the University of New York at Albany, National Cancer Institute.

NIOM is classified by The Polish Ministry of Science and Higher Education as a First Class scientific institution. The Institute has been coordinating works of the EU (FP6/FP7) network of excellence of 25 partners from 14 European countries – ECNIS/ECNIS2, (2005-2013).

The Departments of Environmental Epidemiology, Toxicology and Carcinogenesis, Immunotoxicology, Chemical and Dust Hazards and Health Promotion joined their activities within EPIMOL centre established in 2001 (integral part of NIOM) for better integration of research and problem oriented activities to ensure a comprehensive, multidimensional approach to the assessment of health risk from occupational and environmental exposure to the carcinogenic agents.

The Department of Environmental Epidemiology will perform the leading part of the planned research. The Department has been conducting epidemiological studies on health effects of occupational and environmental hazards, including occupational, environmental and genetic determinants of cancer. It has participated in several multinational, multicentre projects on cancers or occupational exposure to carcinogens, among others IARC coordinated projects on lung, and kidney cancer, NCI funded project on breast, endometrial and ovary cancer, FP5 supported project on the exposure assessment in rubber industry (ExAsRub).

Principal investigator at NIOM: Prof. Beata Pepłońska, MD, PhD